• Introduction

• Search candidate genes for quantitative trait loci (QTL)

• Search candidate genes for diseases

• Search candidate genes for microarray experiments

Step1. Choose QTL module.

Step2. Specify species, chromosome and QTL region. Candidate gene search is now available for 16 species. QTL region can be specified through three ways: two flanking markers, base pairs or peak marker. Please note if the QTL covers a big part of the chromosome, there may be a significant delay while mapping phenotype to genotype.

Step3. Specify database and search strategy. On this page, you should see two search strategy areas, one is for OMIM, another is for PubMed. Each of search strategy area consists of three rows with one search box per row as shown below.

You can enter one or more search key words describing the specific phenotypic features into the search box. Words should be separated by spaces. Enclosing several words in quotation marks causes them to be evaluated as a phrase, such as "bone strength".

By default, words within a text box are combined with a Boolean OR unless otherwise specified by choosing from pull-down menu on the right of the search box.

You can restrict your search to a particular field using the pull-down menus on the left of the search box. The keyword search can be performed on full text, on title and abstract, or on title only for PubMed. In OMIM, it is available for full text, clinical synopsis field, or gene map disorder field.

To construct more complex queries, You can enter multiple words or phrases in the additional search boxes in each row and then select appropriate Boolean operators (AND, OR, NOT) using the pull-down menus on the left to connect the search terms in different search boxes.

For long strategies, click the plus sign at the top left of the search strategy area to add additional rows of search boxes. To remove search boxes, click the minus sign.

You can choose to perform search on PubMed only, OMIM only, or both by setting the check box at the top of the search strategy areas "checked" or "unchecked".

Step1. Choose disease locus module.

Step2. Specify species, chromosome and disease locus region. Candidate gene search is now available for 16 species. Disease locus can be specified through two ways: two flanking markers and base pairs. Please note if the disease locus covers a big part of the chromosome, there may be a significant delay while mapping phenotype to genotype.

Step3. Specify database and search strategy. On this page, you should see two search strategy areas, one is for OMIM, another is for PubMed. Each of search strategy area consists of three rows with one search box per row as shown below.

You can enter one or more search key words describing the specific phenotypic features into the search box. Words should be separated by spaces. Enclosing several words in quotation marks causes them to be evaluated as a phrase, such as "bone strength".

By default, words within a text box are combined with a Boolean OR unless otherwise specified by choosing from pull-down menu on the right of the search box.

You can restrict your search to a particular field using the pull-down menus on the left of the search box. The keyword search can be performed on full text, on title and abstract, or on title only for PubMed. In OMIM, it is available for full text, clinical synopsis field, or gene map disorder field.

To construct more complex queries, You can enter multiple words or phrases in the additional search boxes in each row and then select appropriate Boolean operators (AND, OR, NOT) using the pull-down menus on the left to connect the search terms in different search boxes.

For long strategies, click the plus sign at the top left of the search strategy area to add additional rows of search boxes. To remove search boxes, click the minus sign.

You can choose to perform search on PubMed only, OMIM only, or both by setting the check box at the top of the search strategy areas "checked" or "unchecked".

Step1. Choose microarray module.

Step2. Enter your gene list into text box or upload a plain text file containing one or more genes. Genes should be separated by spaces or newlines.

Step3. Specify database and search strategy. On this page, you should see two search strategy areas, one is for OMIM, another is for PubMed. Each of search strategy area consists of three rows with one search box per row as shown below.

You can enter one or more search key words describing the specific phenotypic features into the search box. Words should be separated by spaces. Enclosing several words in quotation marks causes them to be evaluated as a phrase, such as "bone strength".

By default, words within a text box are combined with a Boolean OR unless otherwise specified by choosing from pull-down menu on the right of the search box.

You can restrict your search to a particular field using the pull-down menus on the left of the search box. The keyword search can be performed on full text, on title and abstract, or on title only for PubMed. In OMIM, it is available for full text, clinical synopsis field, or gene map disorder field.

To construct more complex queries, You can enter multiple words or phrases in the additional search boxes in each row and then select appropriate Boolean operators (AND, OR, NOT) using the pull-down menus on the left to connect the search terms in different search boxes.

For long strategies, click the plus sign at the top left of the search strategy area to add additional rows of search boxes. To remove search boxes, click the minus sign.

You can choose to perform search on PubMed only, OMIM only, or both by setting the check box at the top of the search strategy areas "checked" or "unchecked".